{"id":150823,"date":"2023-09-05T11:00:53","date_gmt":"2023-09-05T09:00:53","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=150823"},"modified":"2023-09-05T11:01:03","modified_gmt":"2023-09-05T09:01:03","slug":"muze-psilocybin-lecit-zavislost-na-hazardnich-hrach","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/cs\/blog\/can-psilocybin-treat-gambling-addiction\/","title":{"rendered":"M\u016f\u017ee psilocybin l\u00e9\u010dit z\u00e1vislost na hazardn\u00edch hr\u00e1ch?"},"content":{"rendered":"

V\u011bdci z Centra pro psychedelick\u00fd v\u00fdzkum na Imperial College v Lond\u00fdn\u011b za\u010dnou zkoumat psilocybin<\/a>-asistovan\u00e1 terapie jako l\u00e9\u010dba porucha hazardn\u00edch her<\/a> v \u0159\u00edjnu tohoto roku s c\u00edlem zlep\u0161it porozum\u011bn\u00ed tomu, jak funkce mozku ovliv\u0148uje tento stav. <\/strong><\/p>\n\n\n\n

Jak hazardn\u00ed hry ovliv\u0148uj\u00ed mozek<\/h2>\n\n\n\n

Hlavn\u00edm c\u00edlem t\u00e9to pr\u016flomov\u00e9 studie je zjistit a zaznamenat zm\u011bny v mozkov\u00e9m syst\u00e9mu odm\u011bn v dob\u011b, kdy se dobrovoln\u00edci v\u011bnuj\u00ed \u010dinnostem spojen\u00fdm s hazardn\u00edmi hrami a podn\u011bty souvisej\u00edc\u00edmi s hazardn\u00edmi hrami. Polovinu dobrovoln\u00edk\u016f budou tvo\u0159it mu\u017ei, kte\u0159\u00ed jsou z\u00e1visl\u00ed na hazardn\u00edch hr\u00e1ch. Druhou polovinu budou tvo\u0159it mu\u017ei stejn\u00e9ho v\u011bku, kte\u0159\u00ed hazardn\u00ed hrou nejsou - tedy \"kontroln\u00ed skupina\".<\/p>\n\n\n\n

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Foto: Erik Mclean on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

P\u0159ed zah\u00e1jen\u00edm studie projdou \u00fa\u010dastn\u00edci zdravotn\u00edm screeningem. Pot\u00e9 jim bude pod\u00e1n psilocybin v kombinaci s terapi\u00ed rozhovorem. Pomoc\u00ed funk\u010dn\u00ed magnetick\u00e9 rezonance (fMRI) <\/em>a elektroencefalografie (EEG) <\/em>v\u00fdzkumn\u00edci budou hodnotit, zda doch\u00e1z\u00ed ke zm\u011bn\u00e1m v mozkov\u00e9m syst\u00e9mu odm\u011bn, zat\u00edmco dobrovoln\u00edci pln\u00ed \u00fakoly spojen\u00e9 s hazardn\u00edmi hrami, a tak\u00e9 p\u0159i sledov\u00e1n\u00ed vide\u00ed souvisej\u00edc\u00edch s hazardn\u00edmi hrami a vide\u00ed nesouvisej\u00edc\u00edch s hazardn\u00edmi hrami. <\/p>\n\n\n\n

Studie by mohla pomoci l\u00e9\u010dit v\u0161echny poruchy z\u00e1vislosti <\/h2>\n\n\n\n

Mezi p\u0159edn\u00ed v\u00fdzkumn\u00e9 pracovn\u00edky pat\u0159\u00ed Profesor David Nutt<\/a>, Dr. Matt Wall, Dr. David Erritzoe a Rayyan Zafar, PhD, z Centra pro psychedelick\u00fd v\u00fdzkum a neuropsychofarmakologii na Imperial College. Jsou optimisti\u010dt\u00ed a v\u011b\u0159\u00ed, \u017ee jim tato studie pom\u016f\u017ee vyvinout lep\u0161\u00ed a \u00fa\u010dinn\u011bj\u0161\u00ed l\u00e9\u010dbu pro osoby trp\u00edc\u00ed poruchami hazardn\u00edho hran\u00ed, stejn\u011b jako v\u0161emi n\u00e1vykov\u00fdmi poruchami. <\/p>\n\n\n\n

Zafar \u0159ekl;<\/p>\n\n\n\n

\"Jsme nad\u0161en\u00ed. Tuto pr\u00e1ci jsme cht\u011bli d\u011blat u\u017e del\u0161\u00ed dobu... Zpo\u010d\u00e1tku to bude p\u011bt pacient\u016f a od p\u0159\u00ed\u0161t\u00edho roku to samoz\u0159ejm\u011b budeme zvy\u0161ovat.\"<\/strong><\/em><\/p>\n\n\n\n

\u010casy se m\u011bn\u00ed<\/h2>\n\n\n\n

Prvn\u00ed klinickou studii sv\u00e9ho druhu na sv\u011bt\u011b bude financovat vl\u00e1da Spojen\u00e9ho kr\u00e1lovstv\u00ed. A\u017e dosud byl psychedelick\u00fd v\u00fdzkum ve Spojen\u00e9m kr\u00e1lovstv\u00ed financov\u00e1n vl\u00e1dou jen velmi m\u00e1lo. Tato nov\u00e1 studie znamen\u00e1 obrovsk\u00fd krok vp\u0159ed v \u0161ir\u0161\u00edm p\u0159ijet\u00ed psychedelick\u00e9 medic\u00edny. <\/p>\n\n\n\n

 \"Mo\u017en\u00e1 je to znamen\u00ed, \u017ee se \u010dasy m\u011bn\u00ed. St\u00e1v\u00e1 se z n\u00ed prioritn\u00ed oblast a u\u017e to nen\u00ed okrajov\u00e1 v\u011bda.\"<\/strong><\/em> Zafar \u0159ekl. <\/p>\n\n\n\n

Tato studie by mohla pomoci p\u0159i v\u00fdvoji l\u00e9\u010dby, kter\u00e1 by v budoucnu mohla b\u00fdt dostupn\u00e1 v r\u00e1mci NHS. N\u00e1rodn\u00ed zdravotn\u00ed slu\u017eba je ve\u0159ejn\u011b financovan\u00fd syst\u00e9m zdravotn\u00ed p\u00e9\u010de ve Spojen\u00e9m kr\u00e1lovstv\u00ed. <\/p>\n\n\n\n

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p\u0159es Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

V\u011bdci tak\u00e9 doufaj\u00ed, \u017ee v\u00fdsledky studie pomohou p\u0159i v\u00fdvoji pokro\u010dilej\u0161\u00edch metod zobrazov\u00e1n\u00ed mozku. Ty by byly schopny sou\u010dasn\u011b m\u011b\u0159it mozkovou aktivitu a molekuly mozkov\u00fdch posl\u00ed\u010dk\u016f. V\u00fdvoj sofistikovan\u011bj\u0161\u00edch technik zobrazov\u00e1n\u00ed mozku p\u0159es\u00e1hne r\u00e1mec v\u00fdzkumu z\u00e1vislost\u00ed - mohl by posunout dop\u0159edu obecnou oblast v\u011bdy o mozku. <\/p>\n\n\n\n

Sou\u010dasn\u00e9 l\u00e9\u010debn\u00e9 postupy jsou velmi \u017e\u00e1douc\u00ed<\/h2>\n\n\n\n

V sou\u010dasn\u00e9 dob\u011b chyb\u00ed l\u00e9\u010dba poruchy hazardn\u00edho hran\u00ed. Zafar vysv\u011btlil;<\/p>\n\n\n\n

\"Sou\u010dasn\u00e9 klinick\u00e9 paradigma l\u00e9\u010dby z\u00e1vislosti na hazardn\u00edch hr\u00e1ch ve Spojen\u00e9m kr\u00e1lovstv\u00ed je psychosoci\u00e1ln\u00ed intervence. Jako je kognitivn\u011b-behavior\u00e1ln\u00ed terapie (CBT), p\u0159i\u010dem\u017e n\u011bkter\u00fdm pacient\u016fm je off-label p\u0159edepisov\u00e1n naltrexon. K dne\u0161n\u00edmu dni neexistuje \u017e\u00e1dn\u00e1 licencovan\u00e1 farmakologick\u00e1 intervence pro l\u00e9\u010dbu poruchy hazardn\u00edho hran\u00ed,\"<\/strong><\/em><\/p>\n\n\n\n

Nast\u00ednil tak\u00e9, jak by tento v\u00fdzkum mohl b\u00fdt p\u0159\u00ednosn\u00fd pro celou \u0159adu onemocn\u011bn\u00ed souvisej\u00edc\u00edch se z\u00e1vislostmi - jak s u\u017e\u00edv\u00e1n\u00edm n\u00e1vykov\u00fdch l\u00e1tek, tak s chov\u00e1n\u00edm. <\/p>\n\n\n\n

\"Vzhledem k podobnostem klinick\u00fdch a mozkov\u00fdch charakteristik mezi z\u00e1vislostmi na u\u017e\u00edv\u00e1n\u00ed n\u00e1vykov\u00fdch l\u00e1tek a z\u00e1vislostmi na chov\u00e1n\u00ed se domn\u00edv\u00e1me, \u017ee psychedelika mohou b\u00fdt schopna p\u016fsobit na stejn\u00e9 psychologick\u00e9 a fyziologick\u00e9 mechanismy, kter\u00e9 jsou z\u00e1kladem tohoto stavu.\"<\/strong><\/em><\/p>\n\n\n\n

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Foto: Aidan Howe on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Psilocybin a v\u00fdzkum z\u00e1vislost\u00ed<\/h2>\n\n\n\n

Pokud sledujete novinky o psychedelik\u00e1ch, v\u00edte, \u017ee v\u00fdzkum potenci\u00e1lu psilocybinu omezit z\u00e1vislost nen\u00ed nov\u00fd. Zde jsou n\u011bkter\u00e9 z nejv\u00fdznamn\u011bj\u0161\u00edch z ned\u00e1vn\u00e9 minulosti:<\/p>\n\n\n\n