{"id":16954,"date":"2021-02-09T08:47:46","date_gmt":"2021-02-09T08:47:46","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=16954"},"modified":"2023-11-07T11:11:28","modified_gmt":"2023-11-07T10:11:28","slug":"muze-lsd-vylecit-stydlivost","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/cs\/blog\/can-lsd-cure-shyness\/","title":{"rendered":"M\u016f\u017ee LSD vyl\u00e9\u010dit plachost?"},"content":{"rendered":"

<\/p>\n\n\n\n

LSD poprv\u00e9 vzalo sv\u011bt \u00fatokem ve swinguj\u00edc\u00edch 60. letech. Ale ani nyn\u00ed, v roce 2021, jsme je\u0161t\u011b neodhalili v\u0161echna jej\u00ed tajemstv\u00ed. Jako nap\u0159\u00edklad jak p\u0159esn\u011b <\/em>podn\u011bcuje LSD mozek ke zkoum\u00e1n\u00ed dosud nep\u0159edstaviteln\u00fdch oblast\u00ed? <\/strong><\/p>\n\n\n\n

N\u011bkte\u0159\u00ed v\u011bdci na\u0161t\u011bst\u00ed pracuj\u00ed na rozlousknut\u00ed tohoto p\u0159\u00edpadu... testuj\u00ed mikrod\u00e1vky LSD, aby za\u017eehli jiskru. prosoci\u00e1ln\u00ed chov\u00e1n\u00ed <\/strong>u my\u0161\u00ed.<\/p>\n\n\n\n

A tak se \u010dlov\u011bk zamysl\u00ed nad t\u00edm, jestli LSD m\u016f\u017ee vyl\u00e9\u010dit plachost a podpo\u0159it spole\u010denskost u d\u011bt\u00ed. lid\u00e9<\/em>, tak\u00e9?<\/p>\n\n\n\n

Zbo\u0159te sv\u00e9 zdi...<\/em><\/h2>\n\n\n\n

V ned\u00e1vn\u00e9m studium<\/strong><\/a>, v\u011bdci zjistili, \u017ee Diethylamid kyseliny lysergov\u00e9<\/strong> (LSD)<\/em> posiluje soci\u00e1ln\u00ed interakci u my\u0161\u00ed. A to d\u011bl\u00e1<\/em> vytvo\u0159it <\/em>smysl,<\/em> \u017ee ano? Koneckonc\u016f LSD je zn\u00e1m\u00e9 svou neuv\u011b\u0159itelnou schopnost\u00ed zcela zbo\u0159it psychick\u00e9 zdi \u010dlov\u011bka.<\/p>\n\n\n\n

P\u0159em\u00fd\u0161lejte o tom. I po 20 minut\u00e1ch v\u00e1s LSD za\u010d\u00edn\u00e1 pohlcovat. pocit naprost\u00e9 d\u016fv\u011bry<\/strong> a blahobytu. <\/strong>Va\u0161e emoce jsou zv\u00fd\u0161en\u00e9 - V\u0160ECHNY, a\u0165 u\u017e dobr\u00e9 nebo \u0161patn\u00e9. Bolestiv\u00e1 bla\u017eenost. N\u00e1dhern\u00e1 hr\u016fza. Ale jedno je jist\u00e9: budete tou\u017eit po spole\u010dnosti lid\u00ed, se kter\u00fdmi budete sd\u00edlet j\u00edzdu. <\/p>\n\n\n\n

A pokud pot\u0159ebujete n\u011bjak\u00fd d\u016fkaz o tom, \u017ee LSD je \"culty\", sta\u010d\u00ed si vzpomenout na psychedelick\u00e9ho hrdinu. Timothy Leary<\/a><\/strong>. <\/strong> Leary zalo\u017eil vlastn\u00ed \"c\u00edrkev\" s n\u00e1zvem Liga pro duchovn\u00ed objevov\u00e1n\u00ed, jej\u00ed\u017e sv\u00e1tost\u00ed bylo LSD. P\u0159\u00edb\u011bh\u016f o skupin\u00e1ch outsider\u016f soust\u0159ed\u011bn\u00fdch kolem t\u00e9to rozd\u011bluj\u00edc\u00ed l\u00e1tky je ve skute\u010dnosti mnoho.<\/p>\n\n\n\n

Tajn\u00e1 om\u00e1\u010dka <\/em><\/h2>\n\n\n\n

Nahum Sonenberg<\/strong>, spoluautor a profesor biochemie na McGillov\u011b univerzit\u011b, uvedl, \u017ee v\u017edy v\u011bd\u011bli, \u017ee LSD vyvol\u00e1v\u00e1 \u0161\u0165astn\u00e9 my\u0161lenky. Ale skute\u010dn\u011b identifikovat \"tajnou om\u00e1\u010dku\", takovou, kter\u00e1 by p\u0159\u00edpadn\u011b mohla vyl\u00e9\u010dit soci\u00e1ln\u00ed \u00fazkost? To jim vyrazilo dech.<\/p>\n\n\n\n

V\u011bdci zjistili, \u017ee LSD zap\u00edn\u00e1 \"sp\u00edna\u010d\" pro serotonin, <\/strong>zn\u00e1m\u00fd tak\u00e9 jako \"hormon \u0161t\u011bst\u00ed\". To vzru\u0161uje siln\u00fd AMPA receptory<\/strong> - s\u00edt\u011b v mozku tak elektrizuj\u00ed, \u017ee mohou zp\u016fsobit epileptick\u00e9 z\u00e1chvaty.<\/p>\n\n\n\n

Co v\u0161ak LSD skute\u010dn\u011b m\u011bn\u00ed, je to, \u017ee probouz\u00ed t\u0159et\u00ed protein, tzv. mTORC 1<\/strong>. A v\u00edte, co se stane, kdy\u017e se v\u0161echny t\u0159i - serotonin, AMPA a mTORC - probud\u00ed sou\u010dasn\u011b? Za\u010dne\u0161 c\u00edtit, jak se ti zved\u00e1 \u017ealudek. Jako by v\u00e1m sv\u011bt pat\u0159il. Jako by ka\u017ed\u00fd je v\u00e1\u0161 p\u0159\u00edtel. <\/em><\/p>\n\n\n\n

\"Dopravn\u00ed
prost\u0159ednictv\u00edm Creative Commons<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Dr. Danilo de Gregorio<\/strong>, prvn\u00ed autor studie a postdoktorand na neurobiologick\u00e9m odd\u011blen\u00ed McGillovy univerzity, \u0159ekl:<\/p>\n\n\n\n

\"Tyto t\u0159i faktory spole\u010dn\u011b podporuj\u00ed soci\u00e1ln\u00ed interakci u my\u0161\u00ed, kter\u00e1 je ekvivalentem empatie a soci\u00e1ln\u00edho chov\u00e1n\u00ed u lid\u00ed.<\/em><\/p>\n\n\n\n

\"Doch\u00e1z\u00ed ke zv\u00fd\u0161en\u00e9 sociabilit\u011b.\"<\/em><\/p>\n\n\n\n

Mikrod\u00e1vka pro Mickeyho<\/em><\/h2>\n\n\n\n

T\u00fdm provedl pokusy na my\u0161\u00edch rozd\u011blen\u00fdch do dvou skupin. <\/p>\n\n\n\n

Prvn\u00ed skupina my\u0161\u00ed dostala mikrod\u00e1vka LSD<\/strong>, opakovan\u011b po dobu 7 dn\u016f. Druh\u00e1 skupina my\u0161\u00ed, co\u017e byla kontroln\u00ed skupina, dostala pouze \"nosi\u010d\". (bez LSD).<\/em> To v\u011bdc\u016fm umo\u017enilo porovnat skupinu spole\u010densk\u00fdch tvor\u016f. s<\/em> LSD, proti jin\u00e9mu bez <\/em>LSD. <\/p>\n\n\n\n

Co se stalo?<\/strong><\/p>\n\n\n\n

\"hn\u011bd\u00e1
Foto: Kanashi on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Pomoc\u00ed metody nazvan\u00e9 optogenetika<\/strong>v\u011bdci provedli na my\u0161\u00edch \u0159adu test\u016f. Do ka\u017ed\u00e9 my\u0161i bylo vlo\u017eeno mal\u00e9 optick\u00e9 vl\u00e1kno. To sledovalo, jak moc jsou \"nabuzen\u00e9\" k socializaci. O sedm dn\u00ed pozd\u011bji byly my\u0161i o\u0161et\u0159eny LSD, aby se zjistilo, jak \u010dasto pozdrav\u00ed kamar\u00e1da - zda v\u016fbec budou m\u00edt radost, \u017ee ho vid\u00ed? A h\u00e1dejte co?<\/p>\n\n\n\n

My\u0161i na kyselin\u011b vynalo\u017een\u00e9<\/strong> v\u00edce \u010dasu s ciz\u00ed my\u0161\u00ed<\/strong>, ve srovn\u00e1n\u00ed s t\u011bmi, kte\u0159\u00ed byli ponech\u00e1ni bez l\u00e9\u010dby. Mohla by b\u00fdt pouh\u00e1 mikrod\u00e1vka* opravdu \u017ee <\/em>tak rychle \u00fa\u010dinn\u00fd? <\/p>\n\n\n\n

(*Zv\u00ed\u0159ata obvykle dost\u00e1vaj\u00ed 100-200 mcg\/kg. V t\u00e9to studii v\u0161ak dost\u00e1vala pouze 30 mcg\/kg denn\u011b, aby se vyhnula halucinac\u00edm.)<\/em><\/p>\n\n\n\n

L\u00e9k na plachost<\/em><\/h2>\n\n\n\n

Jen si p\u0159edstavte, \u017ee by tyto poznatky mohli vyu\u017e\u00edt pro lidi! Je na obzoru l\u00e9k na plachost zalo\u017een\u00fd na LSD? Dr. Gabriella Gobbi<\/strong>, psychiatr a spoluautor studie, si rozhodn\u011b mysl\u00ed, \u017ee je to mo\u017en\u00e9.<\/p>\n\n\n\n

\"Tyto halucinogenn\u00ed slou\u010deniny - kter\u00e9 jsou v n\u00edzk\u00fdch d\u00e1vk\u00e1ch schopny zv\u00fd\u0161it sociabilitu - n\u00e1m mohou pomoci l\u00e9pe porozum\u011bt farmakologii a neurobiologii soci\u00e1ln\u00edho chov\u00e1n\u00ed a v kone\u010dn\u00e9m d\u016fsledku vyvinout a objevit nov\u00e9 a bezpe\u010dn\u011bj\u0161\u00ed l\u00e9ky na du\u0161evn\u00ed poruchy.\"<\/em><\/p>\n\n\n\n

<\/strong>LSD: Syntetick\u00e9 psychedelikum, kter\u00e9 je t\u0159eba porazit?<\/em><\/h2>\n\n\n\n

Psychedelika jsou fantastick\u00fdm zp\u016fsobem \u00faniku z reality. Ne\u017e se v\u0161ak vyd\u00e1te na sv\u016fj \u00fa\u017easn\u00fd v\u00fdlet, v\u011bzte, \u017ee va\u0161e zku\u0161enosti se mohou a budou li\u0161it v z\u00e1vislosti na tom, kter\u00fd halucinogen si vyberete. <\/p>\n\n\n\n

\"Chemick\u00fd
Obr\u00e1zek Colin Behrens z Pixabay<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

LSD je samoz\u0159ejm\u011b laboratorn\u011b vyr\u00e1b\u011bn\u00e9, syntetizovan\u00e9 z n\u00e1melov\u00e9 houby p\u0159ed v\u00edce ne\u017e 80 lety jedn\u00edm Albert Hofmann<\/a>. Na druh\u00e9 stran\u011b psychedelika, kter\u00e1 se vyskytuj\u00ed v p\u0159\u00edrod\u011b, jako nap\u0159. magick\u00e9 houby<\/strong>, kouzeln\u00e9 lan\u00fd\u017ee<\/strong>, ayahuasca a salvia<\/a><\/strong>, by mohly b\u00fdt zkoum\u00e1ny i tyto \u00fa\u010dinky. Chci \u0159\u00edct, \u017ee star\u00fd dobr\u00fd houbov\u00fd trip jist\u011b m\u016f\u017ee vyvolat h\u0159ejivou z\u00e1\u0159i pro cel\u00e9 lidstvo. A cokoli, co n\u00e1m pom\u016f\u017ee, abychom spolu v\u0161ichni l\u00e9pe vych\u00e1zeli, nem\u016f\u017ee b\u00fdt \u0161patn\u00e9, ne?<\/p>\n\n\n\n

Co si mysl\u00edte? C\u00edt\u00edte se p\u0159\u00e1tel\u0161t\u011bji, kdy\u017e jedete v psychedelick\u00e9m vlaku? <\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Kyselina. Blotter. Kalifornsk\u00e9 slunce.\u00a0<\/p>\n

Lucy in the Sky with Diamonds.<\/p>\n

Mo\u017en\u00e1 ji zn\u00e1te podle n\u00e1zv\u016f ulic, kter\u00e9 v televizn\u00edch po\u0159adech sebev\u011bdom\u011b sklo\u0148uj\u00ed jak kreslen\u00ed policejn\u00ed detektivov\u00e9, tak \"pochybn\u00e9 postavy\". Ale a\u0165 u\u017e je jeho p\u0159ezd\u00edvka jak\u00e1koli, jedno je jist\u00e9. A\u0165 u\u017e je to cokoli, v\u0161echna ta z\u00e1hada n\u00e1s nut\u00ed v\u011bd\u011bt v\u00edc!<\/p>","protected":false},"author":4,"featured_media":16959,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[68],"tags":[],"topics":[],"class_list":["post-16954","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"_links":{"self":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/16954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/comments?post=16954"}],"version-history":[{"count":3,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/16954\/revisions"}],"predecessor-version":[{"id":160389,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/16954\/revisions\/160389"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/media\/16959"}],"wp:attachment":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/media?parent=16954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/categories?post=16954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/tags?post=16954"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/topics?post=16954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}