{"id":196977,"date":"2024-06-13T17:48:38","date_gmt":"2024-06-13T15:48:38","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=196977"},"modified":"2024-06-13T17:49:26","modified_gmt":"2024-06-13T15:49:26","slug":"yaleova-univerzita-zkouma-psilocybin-pro-ptsd","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/cs\/blog\/yale-university-to-study-psilocybin-for-ptsd\/","title":{"rendered":"Yaleova univerzita zkoum\u00e1 psilocybin pro l\u00e9\u010dbu posttraumatick\u00e9 stresov\u00e9 poruchy"},"content":{"rendered":"

Od dob, kdy Timothy Leary a Ram Dass \u0159\u00e1dili s LSD a houbi\u010dkami na Harvardu, nejsou univerzity Ivy League spojov\u00e1ny s psychedeliky. (a my v\u00edme. jak to dopadlo<\/a>!) <\/em>Na\u0161t\u011bst\u00ed se nyn\u00ed pro tato ctihodn\u00e1 vzd\u011bl\u00e1vac\u00ed m\u00edsta v\u0161e m\u011bn\u00ed, proto\u017ee i oni<\/em> odklonit se od z\u00e1\u0159iv\u00e9ho potenci\u00e1lu psychedelick\u00e9 renesance.\u00a0<\/strong><\/p>\n\n\n\n

To znamen\u00e1, \u017ee v t\u011bchto vzd\u011bl\u00e1vac\u00edch instituc\u00edch prob\u00edh\u00e1 mnoho zaj\u00edmav\u00fdch psychedelick\u00fdch studi\u00ed. Ten, na kter\u00fd se d\u00edv\u00e1me v tento<\/strong> \u010dl\u00e1nek, je p\u0159ipravovan\u00e1 pilotn\u00ed studie prob\u00edhaj\u00edc\u00ed na Yaleov\u011b univerzit\u011b v New Havenu ve st\u00e1t\u011b Connecticut, kter\u00e1 bude zkoumat p\u0159\u00ednosy syntetick\u00e9ho psilocybinu p\u0159i pod\u00e1v\u00e1n\u00ed osob\u00e1m s du\u0161evn\u00edmi probl\u00e9my, jako je nap\u0159\u00edklad posttraumatick\u00e1 stresov\u00e1 porucha.\u00a0<\/p>\n\n\n\n

\"\"
p\u0159es Wholecelium<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Jak bude studie fungovat?<\/h2>\n\n\n\n

Studijn\u00ed skupinu bude tvo\u0159it 50 pacient\u016f, p\u0159ev\u00e1\u017en\u011b veter\u00e1n\u016f a p\u0159\u00edslu\u0161n\u00edk\u016f prvn\u00ed pomoci, kte\u0159\u00ed trp\u00ed du\u0161evn\u00edmi poruchami, jako jsou deprese a\/nebo z\u00e1vislost. \u00da\u010dastn\u00edci si vezmou 25 mg syntetick\u00e9ho psilocybinu a pot\u00e9, co psychedelick\u00e9 \u00fa\u010dinky za\u010dnou odezn\u00edvat, budou hovo\u0159it s vy\u0161kolen\u00fdmi terapeuty o sv\u00fdch zku\u0161enostech, probl\u00e9mech a pokroc\u00edch.\u00a0<\/p>\n\n\n\n

St\u00e1tn\u00ed poslankyn\u011b Michelle Cookov\u00e1 \u0159ekl den\u00edku Connecticut Post<\/a>, \u017ee c\u00edlem je shrom\u00e1\u017edit st\u00e1tn\u00ed \u00fadaje o psychedelick\u00e9 terapii, kter\u00e9 dosud chyb\u011bly.\u00a0<\/p>\n\n\n\n

\"Pot\u0159ebujeme m\u00edt k dispozici \u00fadaje, kter\u00e9 prok\u00e1\u017e\u00ed, \u017ee existuje zdokumentovan\u00fd d\u016fkaz o tom, co tato terapie d\u011bl\u00e1,\" \u0159ekl. <\/em>Cook vysv\u011btlil. \"V\u00edme, \u017ee m\u00e1 neuv\u011b\u0159iteln\u00e9 v\u00fdsledky, pokud je prov\u00e1d\u011bna spr\u00e1vn\u011b, pokud je prov\u00e1d\u011bna lidmi, kte\u0159\u00ed jsou vy\u0161koleni v tom, jak ji pou\u017e\u00edvat pro l\u00e9\u010dbu posttraumatick\u00e9 stresov\u00e9 poruchy a podobn\u011b.\"<\/em><\/p>\n\n\n\n

\"\"
Studie se z\u00fa\u010dastn\u00ed vojen\u0161t\u00ed veter\u00e1ni (Foto: sydney Rae on Unsplash<\/em>)<\/mark><\/figcaption><\/figure>\n\n\n\n

Probl\u00e9m psilocybinu<\/h3>\n\n\n\n

U\u017e\u00edv\u00e1n\u00ed l\u00e1tek za\u0159azen\u00fdch do seznamu 1 v klinick\u00e9m prost\u0159ed\u00ed se pot\u00fdk\u00e1 s \u0159adou jedine\u010dn\u00fdch probl\u00e9m\u016f - za prv\u00e9, nem\u016f\u017eete vyu\u017e\u00edt poji\u0161t\u011bn\u00ed. V\u00fdzkumn\u00edk z Yaleovy univerzity Ben Kelmendi (kter\u00fd se chyst\u00e1 zah\u00e1jit v\u00fd\u0161e uvedenou pilotn\u00ed studii). <\/em>\u0159ekl; \u00a0<\/em><\/p>\n\n\n\n

\"I kdy\u017e se jedn\u00e1 o v\u00fdzkumn\u00fd program, l\u00e9\u010d\u00edte je klinicky. A abyste je mohli l\u00e9\u010dit klinicky, mus\u00edte m\u00edt kryt\u00ed za zneu\u017eit\u00ed pr\u00e1va,\" \u0159ekl.\u00a0<\/em><\/p>\n\n\n\n

To znamen\u00e1, \u017ee v\u00fdzkum l\u00e9\u010debn\u00fdch \u00fa\u010dink\u016f psilocybinu byl kv\u016fli z\u00e1konn\u00fdm omezen\u00edm v\u00e1\u017en\u011b naru\u0161en. P\u0159\u00edpustn\u00e9 jsou pouze ur\u010dit\u00e9 podm\u00ednky. Nap\u0159\u00edklad posttraumatick\u00e1 stresov\u00e1 porucha je slo\u017eit\u00fd stav, kter\u00fd nem\u00e1 definitivn\u00ed a spolehlivou l\u00e9\u010dbu. To znamen\u00e1, \u017ee v\u00fdzkum l\u00e9\u010dby pomoc\u00ed \"m\u00e9n\u011b obvykl\u00fdch\" metod je pova\u017eov\u00e1n za \"p\u0159ijateln\u00fd\".\u00a0\u00a0<\/p>\n\n\n\n

Je d\u016fle\u017eit\u00e9 poznamenat, \u017ee tato studie pou\u017e\u00edv\u00e1 \"syntetick\u00fd psilocybin\". A to navzdory skute\u010dnosti, \u017ee ned\u00e1vn\u00e1 studie zjistila, \u017ee p\u0159\u00edrodn\u00ed psilocybin (p\u0159\u00edmo z houby) <\/em>je ve skute\u010dnosti \u00fa\u010dinn\u011bj\u0161\u00ed a prosp\u011b\u0161n\u011bj\u0161\u00ed. <\/a><\/strong><\/p>\n\n\n\n

Posttraumatick\u00e1 stresov\u00e1 porucha je t\u011b\u017eko l\u00e9\u010diteln\u00e1 - mohl by b\u00fdt kl\u00ed\u010dem psilocybin?<\/h4>\n\n\n\n

Kelmendi tuto nal\u00e9havost zd\u016fraznil;<\/p>\n\n\n\n

\"U veter\u00e1n\u016f se st\u00e1v\u00e1, \u017ee nevyhledaj\u00ed l\u00e9\u010dbu hned... Za\u010dnou se obracet k alkoholu nebo jin\u00fdm l\u00e1tk\u00e1m, tak\u017ee te\u010f maj\u00ed komorbiditu, a ta je<\/em> - co\u017e je ve skute\u010dnosti jejich vlastn\u00ed zp\u016fsob zvl\u00e1d\u00e1n\u00ed - je ze studie vylou\u010d\u00ed. Jsou to skute\u010dn\u00ed pacienti, kte\u0159\u00ed skute\u010dn\u011b trp\u00ed a kte\u0159\u00ed skute\u010dn\u011b pot\u0159ebuj\u00ed pomoc. Nemohou se k t\u011bmto l\u00e9k\u016fm dostat, proto\u017ee neodpov\u00eddaj\u00ed tomuto profilu \"cookie-cutter\".\"\u00a0<\/em><\/p>\n\n\n\n

\u00dapln\u00fd dopad posttraumatick\u00e9 stresov\u00e9 poruchy je obt\u00ed\u017en\u00e9 vy\u010d\u00edslit, proto\u017ee ovliv\u0148uje v\u00edce aspekt\u016f ka\u017edodenn\u00edho \u017eivota \u010dlov\u011bka.\u00a0<\/p>\n\n\n\n

\"Neexistuje jedin\u00e1 stupnice, kter\u00e1 by skute\u010dn\u011b vystihovala komplexnost ka\u017edodenn\u00edho funk\u010dn\u00edho posti\u017een\u00ed. Je to vlastn\u011b index n\u011bkolika r\u016fzn\u00fdch stupnic,\"<\/em> Kelmendi\u00a0 said. \"Jedn\u00edm z nich jsou zame\u0161kan\u00e9 dny v pr\u00e1ci, produktivita a vztahy, prost\u011b ka\u017edodenn\u00ed \u017eivot. Mysl\u00edm, \u017ee to je mnohem d\u016fle\u017eit\u011bj\u0161\u00ed ne\u017e \u0159\u00edkat: 'Aha, zlep\u0161ily se va\u0161e p\u0159\u00edznaky posttraumatick\u00e9 stresov\u00e9 poruchy, nebo ne?'\"<\/em><\/p>\n\n\n\n

\"\"
Posttraumatick\u00e1 stresov\u00e1 porucha m\u016f\u017ee ovlivnit v\u00edce oblast\u00ed \u017eivota \u010dlov\u011bka. (Foto: K. Mitch Hodge na Unsplash)<\/em><\/mark><\/figcaption><\/figure>\n\n\n\n
\u017d\u00e1dn\u00e1 \"hrdinsk\u00e1 d\u00e1vka\", ale rozhodn\u011b v\u00fdlet<\/h5>\n\n\n\n

V nadch\u00e1zej\u00edc\u00ed studii budou \u00fa\u010dastn\u00edci u\u017e\u00edvat 25 mg syntetick\u00e9ho psilocybinu. (co\u017e je dost na to, aby to vyvolalo psychedelick\u00fd z\u00e1\u017eitek, i kdy\u017e mo\u017en\u00e1 ne \u00fapln\u00fd v\u00fdbuch do vesm\u00edru!) <\/em>N\u00e1sledn\u011b absolvuj\u00ed samostatn\u011b veden\u00e9 terapeutick\u00e9 sezen\u00ed v p\u0159\u00edjemn\u00e9m a relaxa\u010dn\u00edm prost\u0159ed\u00ed. P\u0159ibli\u017en\u011b o 6 hodin pozd\u011bji \u00fa\u010dastn\u00edci absolvuj\u00ed psychoterapeutick\u00e9 sezen\u00ed.\u00a0<\/p>\n\n\n\n

\"Dvacet p\u011bt miligram\u016f se pova\u017euje za m\u00edrnou d\u00e1vku. Nen\u00ed to heroick\u00e1 d\u00e1vka<\/a> nutn\u011b, ale ur\u010dit\u011b je to psychoaktivn\u00ed d\u00e1vka,\".<\/em> Kelmendi vysv\u011btluje. \"Nedirektivn\u00ed podp\u016frn\u00e1 psychoterapie m\u00e1 b\u00fdt prov\u00e1d\u011bna sp\u00ed\u0161e po pod\u00e1n\u00ed d\u00e1vky ne\u017e v jej\u00edm pr\u016fb\u011bhu.\"<\/em><\/p>\n\n\n\n

Vzru\u0161uj\u00edc\u00ed potenci\u00e1l psilocybinu<\/h3>\n\n\n\n

Krom\u011b t\u00e9to p\u0159ipravovan\u00e9 studie prob\u00edh\u00e1 na Yaleov\u011b univerzit\u011b v r\u00e1mci Yaleova programu pro psychedelickou v\u011bdu n\u011bkolik studi\u00ed o psilocybinu. Pat\u0159\u00ed mezi n\u011b studie zam\u011b\u0159en\u00e9 na velkou depresivn\u00ed poruchu. (MDD)<\/em>, obsedantn\u011b kompulzivn\u00ed porucha (OCD), <\/em>migr\u00e9ny, clusterov\u00e9 bolesti hlavy a posttraumatick\u00e9 bolesti hlavy. V roce 2022 zpr\u00e1va<\/a> kterou vydala pracovn\u00ed skupina pod veden\u00edm Connecticutsk\u00e9ho ministerstva pro du\u0161evn\u00ed zdrav\u00ed a slu\u017eby v oblasti z\u00e1vislost\u00ed, v n\u00ed\u017e se jasn\u011b hovo\u0159\u00ed o potenci\u00e1lu psilocybinu jako l\u00e9\u010debn\u00e9ho prost\u0159edku a uv\u00e1d\u00ed se v n\u00ed, \u017ee; \"V\u00fdzkum ukazuje, \u017ee psilocybin je slibnou l\u00e9\u010dbou n\u011bkter\u00fdch stav\u016f chov\u00e1n\u00ed, v\u010detn\u011b u\u017e\u00edv\u00e1n\u00ed n\u00e1vykov\u00fdch l\u00e1tek, deprese a paliativn\u00ed p\u00e9\u010de p\u0159i \u00fazkosti a depresi na konci \u017eivota.\"<\/em><\/p>\n\n\n\n

Krom\u011b toho byl ned\u00e1vno publikov\u00e1n v\u00fdzkum, kter\u00fd nazna\u010duje, \u017ee i lid\u00e9, kte\u0159\u00ed neu\u017e\u00edvaj\u00ed psilocybin z l\u00e9\u010debn\u00fdch d\u016fvod\u016f, maj\u00ed z hlediska du\u0161evn\u00edho zdrav\u00ed st\u00e1le prosp\u011bch. (co\u017e by v\u00e1m mohl \u0159\u00edct ka\u017ed\u00fd psychonaut, kter\u00fd stoj\u00ed za houbi\u010dky!) <\/em>The studium<\/a>, zve\u0159ejn\u011bn\u00e9 loni v z\u00e1\u0159\u00ed, zjistila, \u017ee u\u017e\u00edv\u00e1n\u00ed psilocybinu mimo klinick\u00e9 prost\u0159ed\u00ed (tj. rekrea\u010dn\u011b) <\/em>byla spojena s p\u0159\u00edzniv\u00fdmi \u00fa\u010dinky na du\u0161evn\u00ed zdrav\u00ed, v\u010detn\u011b sn\u00ed\u017een\u00ed depres\u00ed a \u00fazkosti. V\u00fdzkum, kter\u00fd byl publikov\u00e1n v \u010dasopise Frontiers in Psychiatry, <\/em>analyzoval t\u00e9m\u011b\u0159 3000 zpr\u00e1v o zku\u0161enostech lid\u00ed, kte\u0159\u00ed u\u017e\u00edvali magick\u00e9 houby pro sebepozn\u00e1n\u00ed a pot\u011b\u0161en\u00ed. <\/p>\n\n\n\n

Po prostudov\u00e1n\u00ed \u00fadaj\u016f v\u011bdci zjistili, \u017ee \u00fa\u010dastn\u00edci zaznamenali dlouhodob\u00fd pokles depres\u00ed, \u00fazkosti, zneu\u017e\u00edv\u00e1n\u00ed alkoholu, neuroticismu a vyho\u0159en\u00ed. Krom\u011b toho \u00fa\u010dastn\u00edci uv\u00e1d\u011bli zlep\u0161en\u00ed v oblasti emo\u010dn\u00ed regulace, duchovn\u00ed pohody, kognitivn\u00ed flexibility a extraverze.\u00a0<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Zd\u00e1 se jist\u00e9, \u017ee k t\u00e9to studii se letos v l\u00e9t\u011b na Yaleu p\u0159ipoj\u00ed i dal\u0161\u00ed, kter\u00e1 se za\u0159ad\u00ed na rostouc\u00ed hromadu v\u00fdzkum\u016f, je\u017e upozor\u0148uj\u00ed na vzru\u0161uj\u00edc\u00ed potenci\u00e1l psilocybinu.<\/p>","protected":false},"excerpt":{"rendered":"

Zd\u00e1 se, \u017ee na Yaleov\u011b univerzit\u011b bude letos psychedelick\u00e9 l\u00e9to, proto\u017ee v\u011bdci zah\u00e1j\u00ed pilotn\u00ed program zkoumaj\u00edc\u00ed p\u0159\u00ednos syntetick\u00e9ho psilocybinu pro posttraumatickou stresovou poruchu (PTSD).\u00a0<\/p>","protected":false},"author":4,"featured_media":196988,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[67,88],"tags":[],"topics":[],"class_list":["post-196977","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-politics-legislation","category-psychedelic-studies"],"_links":{"self":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/196977","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/comments?post=196977"}],"version-history":[{"count":6,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/196977\/revisions"}],"predecessor-version":[{"id":196995,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/196977\/revisions\/196995"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/media\/196988"}],"wp:attachment":[{"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/media?parent=196977"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/categories?post=196977"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/tags?post=196977"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.wholecelium.com\/cs\/wp-json\/wp\/v2\/topics?post=196977"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}