{"id":22726,"date":"2021-08-07T10:25:13","date_gmt":"2021-08-07T10:25:13","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=18798"},"modified":"2023-11-10T18:11:08","modified_gmt":"2023-11-10T17:11:08","slug":"psilocibinas-augina-naujas-nervu-jungtis","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/lt\/blog\/psilocybin-grows-new-neural-conections\/","title":{"rendered":"Psilocibinas augina naujas nerv\u0173 jungtis"},"content":{"rendered":"\n

By prescribing costly antidepressants at a premium<\/a>, which often do not suit the individual. Not to mention risky side effects such as tiredness, nausea, and loss of creativity. Who wants that?<\/strong><\/p>\n\n\n\n

But, here\u2019s psychedelics to the rescue! The rise of psychedelics has opened up the possibility of more effective ways to treat mental conditions\u2026 Whether you take \u2018em full on, or simply microdose, psychedelics help you process the pain \u2014 without masking the cause.\u00a0<\/p>\n\n\n\n

Take psilocybin<\/strong>, for example: the active compound in magic mushrooms and truffles. Most people know shrooms for their mind-expanding trips. Yet its rewards go a whole lot further! From bursts of creative inspiration, to full-blown mystical experiences. And for years, scientists have studied psilocybin as a potential cure for depression. But they could never pin down exactly what makes it so darn effective\u2026<\/p>\n\n\n\n

Up until now.\u00a0<\/p>\n\n\n\n

Lost and Found: Neural Connections <\/em><\/h2>\n\n\n\n
\"brain
Not just a \u201cspiritual\u201d condition. Depression can snip away brain connections for good, if left untreated. Lucky for us, magic mushrooms and truffles can grow new o<\/mark><\/em>nes!<\/em> via Creative Commons<\/mark><\/figcaption><\/figure>\n\n\n\n

In a new study from Yale, scientists have found that a single dose of psilocybin can grow new neural connections<\/a><\/strong> in the brain. It\u2019s a physical <\/em>change on mice, not just emotional \u2014 hinting at a long-term cure for mental conditions such as depression. Even senior author Alex Kwan<\/strong>, Yale associate professor of psychiatry and neuroscience, was shocked by the results:<\/p>\n\n\n\n

\u201cIt was a real surprise to see such enduring changes from just one dose of psilocybin. These new connections may be the structural changes the brain uses to store new experiences.<\/em><\/p>\n\n\n\n

\u201cWe not only saw a 10% increase in the number of neuronal connections, but also they were on average about 10% larger, so the connections were stronger as well.\u201d<\/em><\/p>\n\n\n\n

The paper was published on July 5 in the journal Neuron.<\/p>\n\n\n\n

Real Recovery from Depression <\/em><\/h2>\n\n\n\n

The researchers were curious about the effects of psilocybin in the prefrontal cortex<\/strong>. Here\u2019s why. When you\u2019re depressed or under a lot of stress, your brain loses a ton<\/em> of neuronal connections in this area. This loss, called synaptic atrophy<\/strong>, is what antidepressants try to fix or \u201cglue back together\u201d \u2014 which doesn\u2019t always last for long.<\/p>\n\n\n\n

\u201cIt is well established that structural neuroplasticity in the [brain] is the key to the action of antidepressants.\u201d<\/em><\/p>\n\n\n\n

Most psychedelics, such as magic mushrooms and truffles, are serotonergic<\/strong>. They can alter your perception, thinking, and mood, and raise your consciousness to a whole \u2018nother level. But what makes psilocybin-based therapy so special is its sustained effect <\/em>on the brain \u2014 lasting for weeks, months, or even longer:<\/p>\n\n\n\n

\u201cAmong serotonergic psychedelics, psilocybin is recently shown to relieve depression symptoms rapidly…with sustained benefits for several months.\u201d<\/em><\/p>\n\n\n\n

It\u2019s not just depression, either. Shrooms and truffles can help treat other neuropsychiatric disorders, such as addiction <\/strong>and obsessive compulsive disorder (OCD<\/a>)<\/strong>. And when combined with talk therapy, the results can last even longer<\/em>. This is why the FDA granted \u201cbreakthrough therapy\u201d <\/strong> status to psilocybin back in 2019. The potential for mental health is just too dang powerful to ignore!<\/p>\n\n\n\n

A Cure That Lasts Longer<\/em><\/h2>\n\n\n\n
\"brain
via Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Today, more and more trials are being done for psilocybin \u2014 at least in treating major depressive disorder. Scientists had proven in the past that magic mushrooms (and ketamine)<\/em> can reduce symptoms of depression. The new paper from Yale goes even further: that psilocybin can literally <\/em>grow new dendritic spines<\/strong>, which look like \u201cbranches”. These spines link brain cells to one another. Stress and depression can zap these connections away\u2026 which makes creative thinking (or let\u2019s face it, even basic tasks)<\/em> a massive pain in the butt.\u00a0<\/p>\n\n\n\n

So how<\/em> exactly did they prove that psilocybin can give long-lasting results? <\/p>\n\n\n\n

Why, this<\/em> is how!<\/p>\n\n\n\n

First, Kwan and his team took photos of dendritic spines \u2014 in the brains of living mice! \u2014 using a laser-scanning microscope<\/strong>. The images were in HD, and captured over a number of days.\u00a0<\/p>\n\n\n\n

Next, they compared the photos before and after they gave the mice psilocybin. What they found after 24 hours was incredible: a dramatic increase<\/strong> in new dendritic spines. Not just more<\/em>, but bigger, too! Here\u2019s the kicker. The new \u201cbranches\u201d were still there a month later. <\/strong>The mice became calmer and friendlier to each other. Their brains also showed a rise in thinking <\/em>habits after being given psilocybin.\u00a0<\/p>\n\n\n\n

\u201cPsilocybin-induced neural plasticity could prime the brain for [adding] new psychological experiences.\u201d<\/em><\/p>\n\n\n\n

\"mouse<\/figure>\n\n\n\n

Not Just For Mystics<\/em><\/h2>\n\n\n\n

Magic mushrooms and truffles <\/strong>are beloved for their trip-inducing properties.\u00a0 Indigenous shamans have prized psilocybin for thousands of years. <\/em>Even to this day, shrooms (along with ayahuasca)<\/em> are a staple of many religious ceremonies. Not quite ready to dive in? That\u2019s okay! Maybe microdosing is for you.<\/a><\/strong> <\/p>\n\n\n\n

Take a potent enough dose, however, and you may even get a profound mystical experience<\/strong>. Not just out-of-body switcheroos, either. We\u2019re talking soul-shaking, life-altering visions of your past, present, and future… all at once. And with this latest discovery in mind, there\u2019s even more reason to love these fantastic fungi. (A potential long-term cure for depression? Heck yeah!)<\/em><\/p>\n\n\n\n

Psilocybin Saves Lives<\/em><\/h2>\n\n\n\n
\"\"
All aboard S.S. Shrooma!\u00a0<\/span><\/strong><\/figcaption><\/figure>\n\n\n\n

Science has gone a looong way in treating serious mental conditions, such as depression, anxiety, and PTSD. From soul-searching sessions in talk therapy, to prescription drugs that often have negative effects. \u201cOf course you don\u2019t feel sad anymore, or any other emotion for that matter. You\u2019re numb!\u201d <\/em>Sure, antidepressants can relieve your mental pain if only for a short while. A Band-Aid solution for a soul drowning in darkness. Or a chemical \u201crubber duckie\u201d of sorts, when what you really need is a boat…\u00a0<\/p>\n\n\n\n

So lets make that boat a shroom ship \u2014 of fresh magic mushrooms and truffles!<\/strong> Psilocybin is a natural lifesaver that does more than simply keep you afloat. It helps you move forward.<\/em>\u00a0<\/p>\n\n\n\n

<\/p>\n\n\n\n

.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"

Depresija yra vampyras. Ji be jokio gailes\u010dio \u017ealoja \u017emogaus sveikat\u0105, santykius ir net finansus. Ar \u017einojote, kad \"Big Pharma\" i\u0161 psichikos sveikatos kriz\u0117s u\u017edirbo milijardus?<\/p>","protected":false},"author":4,"featured_media":22568,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[88],"tags":[],"topics":[],"class_list":["post-22726","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-psychedelic-studies"],"_links":{"self":[{"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/posts\/22726","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/comments?post=22726"}],"version-history":[{"count":2,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/posts\/22726\/revisions"}],"predecessor-version":[{"id":161347,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/posts\/22726\/revisions\/161347"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/media\/22568"}],"wp:attachment":[{"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/media?parent=22726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/categories?post=22726"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/tags?post=22726"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.wholecelium.com\/lt\/wp-json\/wp\/v2\/topics?post=22726"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}