{"id":249108,"date":"2025-09-11T20:13:55","date_gmt":"2025-09-11T18:13:55","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=249108"},"modified":"2025-09-11T20:13:56","modified_gmt":"2025-09-11T18:13:56","slug":"this-swiss-psychiatrist-believes-psychedelics-rewire-the-brain-for-the-better","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/nl\/blog\/this-swiss-psychiatrist-believes-psychedelics-rewire-the-brain-for-the-better\/","title":{"rendered":"This Swiss Psychiatrist Believes Psychedelics Rewire the Brain for the Better"},"content":{"rendered":"<p style=\"font-size:20px\"><strong>For millions struggling with depression, PTSD, or addiction, the current menu of treatments can feel\u2026 well, a little stale. Medications often take weeks to kick in, and even then, relief can be fleeting. For those with treatment-resistant symptoms, it\u2019s like knocking on a locked door over and over again.<\/strong><\/p>\n\n\n\n<p>But \u2014 what if there\u2019s a way to pick that dusty old lock?<\/p>\n\n\n\n<p>That\u2019s where Swiss psychiatrist <strong><a href=\"https:\/\/en.wikipedia.org\/wiki\/Gregor_Hasler\" target=\"_blank\" rel=\"noreferrer noopener\">Gregor Hasler<\/a><\/strong> comes in. In a recent chat with <em><a href=\"https:\/\/genomicpress.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">Genomic Press<\/a><\/em>, Hasler shared how psychedelics like psilocybin, LSD, and MDMA might do something far more radical than conventional meds: they may actually <strong>reorganize brain function<\/strong>. And in doing so, they could offer deeper, longer-lasting healing.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"200\" height=\"150\" src=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/brain-gif-2.gif\" alt=\"\" class=\"wp-image-243575\" style=\"width:656px;height:auto\"><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-meet-the-man-bridging-neuroscience-and-psychedelics\">Meet the Man Bridging Neuroscience and Psychedelics<\/h2>\n\n\n\n<p>Hasler wears a lot of hats. He\u2019s Chair of Psychiatry at the University of Fribourg, directs its <strong>Molecular Psychiatry Laboratory<\/strong>, and has a background that fuses psychoanalysis with hardcore neuroscience. He cut his teeth at the U.S. <strong>Nationaal Instituut voor Geestelijke Gezondheid<\/strong>, where mentors encouraged him to focus on substances that don\u2019t just mask symptoms, but create <strong>rapid, robust shifts<\/strong> in de hersenen.<\/p>\n\n\n\n<p>En <strong>psychedelica<\/strong> fit that bill.<\/p>\n\n\n\n<p>Hasler doesn\u2019t see them as \u201chappy pills\u201d or temporary band-aids. Instead, he describes them as <strong>catalysts for neuroplasticity<\/strong>, that beautiful brain process where neurons form new connections and break out of old, rigid patterns. In other words, psychedelics might help the brain stop playing the same depressing song on repeat and learn some fresh tunes.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"638\" height=\"333\" src=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/small-magic-mushroom-in-hand.jpg\" alt=\"\" class=\"wp-image-98029\" style=\"width:800px;height:auto\" srcset=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/small-magic-mushroom-in-hand.jpg 638w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/small-magic-mushroom-in-hand-300x157.jpg 300w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/small-magic-mushroom-in-hand-18x9.jpg 18w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/small-magic-mushroom-in-hand-600x313.jpg 600w\" sizes=\"(max-width: 638px) 100vw, 638px\" \/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">via Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-switzerland-where-mental-health-meets-innovation\">Switzerland: Where Mental Health Meets Innovation<\/h3>\n\n\n\n<p>It\u2019s no accident this research is happening in Switzerland. The country has a rich history of psychiatric breakthroughs. From early antidepressants and benzos to, of course, Albert Hofmann\u2019s serendipitous <a href=\"https:\/\/www.wholecelium.com\/nl\/blog\/the-definitive-guide-to-celebrating-bicycle-day-2025\/\" target=\"_blank\" rel=\"noreferrer noopener\">ontdekking van LSD<\/a>.<\/p>\n\n\n\n<p>Hasler\u2019s own work builds on that legacy. By studying <strong><a href=\"https:\/\/en.wikipedia.org\/wiki\/Glutamate_(neurotransmitter)\" target=\"_blank\" rel=\"noreferrer noopener\">glutamaat<\/a><\/strong> en <a href=\"https:\/\/en.wikipedia.org\/wiki\/GABA\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>GABA<\/strong> <\/a>neurotransmitter systems, he\u2019s helped reshape how scientists think about mood disorders. He even identified <strong>mGluR5<\/strong> as a biomarker tied to neuroplasticity and nicotine dependence \u2014 a neat bridge between lab science and real-world treatment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-the-science-of-rapid-rewiring\">The Science of Rapid Rewiring<\/h3>\n\n\n\n<p>Here\u2019s the kicker: while antidepressants usually take weeks <em>(or months)<\/em> to make a dent, psychedelic therapy often sparks noticeable change after a hand-full of sessions<em> <\/em>\u2014 often, even just <a href=\"https:\/\/www.wholecelium.com\/nl\/blog\/one-dose-of-psychedelic-boosts-brain-flexibility-for-weeks-study-finds\/\" target=\"_blank\" rel=\"noreferrer noopener\">een<\/a>. <\/p>\n\n\n\n<p>Some participants in studies report improvements that last not just for months, but in some cases, <strong>years<\/strong>. That\u2019s because, according to Hasler, psychedelics don\u2019t just reduce the symptoms. They can actually <strong>reshape the architecture of the brain<\/strong>.<\/p>\n\n\n\n<p>Think of it this way: traditional meds tidy up the living room while leaving the locked attic untouched. Psychedelics, on the other hand, might just hand you the key to the attic, and a chance to reorganize the whole house.<\/p>\n\n\n\n<p>This is why researchers are eyeing psychedelic therapy not only for depression and PTSD, but also for <a href=\"https:\/\/www.wholecelium.com\/nl\/blog\/can-one-single-dose-of-psilocybin-treat-alcoholism\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>addiction recovery<\/strong> <\/a>en zelfs <strong>post-stroke rehabilitation<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"640\" height=\"380\" src=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/wires-brain-rewire.jpg\" alt=\"\" class=\"wp-image-249113\" style=\"width:800px;height:auto\" srcset=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/wires-brain-rewire.jpg 640w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/wires-brain-rewire-300x178.jpg 300w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/wires-brain-rewire-18x12.jpg 18w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/wires-brain-rewire-600x356.jpg 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><figcaption class=\"wp-element-caption\"><em><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-cyan-bluish-gray-color\">Photo by Nathan Cima on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-caution-handle-with-care\">Caution: Handle With Care<\/h4>\n\n\n\n<p>Of course, Hasler is careful to separate rigorous clinical research from the hype around legalization. As President of the <strong>Swiss Society for Drug Safety in Psychiatry<\/strong> <em>(say that five times fast)<\/em> and a member of the <strong>American College of Neuropsychopharmacology<\/strong>, he\u2019s a big advocate for balance: maximum benefit, minimum risk.<\/p>\n\n\n\n<p>Translation? Safety, proper training, and ethical guidelines are non-negotiable. His lab is working to build the protocols needed so psychedelic therapy can one day slot responsibly into mainstream healthcare systems \u2014without cutting corners.<\/p>\n\n\n\n<figure class=\"wp-block-image alignright size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25.png\" alt=\"\" class=\"wp-image-249114\" style=\"width:409px;height:auto\" srcset=\"https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25.png 1000w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25-300x300.png 300w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25-150x150.png 150w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25-768x768.png 768w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25-12x12.png 12w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25-600x600.png 600w, https:\/\/www.wholecelium.com\/wp-content\/uploads\/19-25-100x100.png 100w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-why-this-work-matters\">Why This Work Matters<\/h5>\n\n\n\n<p>For Hasler, this isn\u2019t just professional, it\u2019s personal. Inspired by his father, a mathematician and economist, he\u2019s always seen depression as both a human and economic burden. Improving mental health, he believes, is one of the most impactful contributions science can make to society.<\/p>\n\n\n\n<p>And psychedelics, with their potential to spark <strong>faster, deeper, longer-lasting healing<\/strong>, might just be a cornerstone of that contribution.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-final-thoughts\">Final Thoughts<\/h3>\n\n\n\n<p>Dr. Gregor Hasler isn\u2019t claiming psychedelics are magic bullets \u2014 but his research suggests they might just be the <strong>rewiring tools<\/strong> we\u2019ve been waiting for. With careful protocols, safety nets, and respect for their power, psychedelics could shift from fringe curiosity to frontline treatment for some of the toughest mental health challenges.<\/p>\n\n\n\n<p style=\"font-size:20px\">From Hofmann\u2019s lab in Basel to cutting-edge clinics today, Switzerland\u2019s psychedelic journey comes full circle. And if Hasler\u2019s work is any sign, the future of psychiatry could be looking a lot more\u2026 neuroplastic.<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Hailing from Switzerland \u2014 the country of psychedelic breakthroughs \u2014 Psychiatrist Gregor Hasler has a lot to say about the potential of substances like psilocybin to change the mental health treatment field forever. <\/p>","protected":false},"author":4,"featured_media":249473,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[67,69],"tags":[],"topics":[],"class_list":["post-249108","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-politics-legislation","category-psychedelic-culture"],"_links":{"self":[{"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/posts\/249108","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/comments?post=249108"}],"version-history":[{"count":3,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/posts\/249108\/revisions"}],"predecessor-version":[{"id":249116,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/posts\/249108\/revisions\/249116"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/media\/249473"}],"wp:attachment":[{"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/media?parent=249108"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/categories?post=249108"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/tags?post=249108"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.wholecelium.com\/nl\/wp-json\/wp\/v2\/topics?post=249108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}