{"id":16954,"date":"2021-02-09T08:47:46","date_gmt":"2021-02-09T08:47:46","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=16954"},"modified":"2023-11-07T11:11:28","modified_gmt":"2023-11-07T10:11:28","slug":"moze-lsd-liecit-plachost","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/sk\/blog\/can-lsd-cure-shyness\/","title":{"rendered":"M\u00f4\u017ee LSD vylie\u010di\u0165 plachos\u0165?"},"content":{"rendered":"

<\/p>\n\n\n\n

LSD sa prv\u00fdkr\u00e1t dostalo do povedomia sveta v 60. rokoch 20. storo\u010dia. Ale ani teraz, v roku 2021, sme e\u0161te neodhalili v\u0161etky jeho tajomstv\u00e1. Ako napr\u00edklad, ako presne <\/em>podnecuje LSD mozog k objavovaniu oblast\u00ed, ktor\u00e9 si predt\u00fdm nevedel predstavi\u0165? <\/strong><\/p>\n\n\n\n

Na\u0161\u0165astie sa niektor\u00ed vedci sna\u017eia tento pr\u00edpad rozl\u00fasknu\u0165... testuj\u00fa mikrod\u00e1vky LSD, aby vyvolali prosoci\u00e1lne spr\u00e1vanie <\/strong>u my\u0161\u00ed.<\/p>\n\n\n\n

A tak sa \u010dlovek za\u010dne zam\u00fd\u0161\u013ea\u0165 nad t\u00fdm, \u010di LSD dok\u00e1\u017ee vylie\u010di\u0165 plachos\u0165 a podpori\u0165 spolo\u010denskos\u0165 u \u013eudia<\/em>, ako aj?<\/p>\n\n\n\n

Zb\u00farajte svoje steny...<\/em><\/h2>\n\n\n\n

V ned\u00e1vnom \u0161t\u00fadium<\/strong><\/a>, v\u00fdskumn\u00edci zistili, \u017ee Dietylamid kyseliny lysergovej<\/strong> (LSD)<\/em> zv\u00fd\u0161ila soci\u00e1lnu interakciu u my\u0161\u00ed. A to rob\u00ed<\/em> vytvori\u0165 <\/em>zmysel,<\/em> nie? Koniec koncov, LSD je zn\u00e1me svojou neuverite\u013enou schopnos\u0165ou \u00faplne zb\u00fara\u0165 psychick\u00e9 steny \u010dloveka.<\/p>\n\n\n\n

Prem\u00fd\u0161\u013eajte o tom. U\u017e po 20 min\u00fatach v\u00e1s LSD za\u010dne pohlcova\u0165 pocit \u00faplnej d\u00f4very<\/strong> a blahobyt. <\/strong>Va\u0161e em\u00f3cie s\u00fa zv\u00fd\u0161en\u00e9 - V\u0160ETKY, dobr\u00e9 aj zl\u00e9. Bolestiv\u00e1 bla\u017eenos\u0165. N\u00e1dhern\u00e1 hr\u00f4za. Ale jedno je celkom ist\u00e9: budete t\u00fa\u017ei\u0165 po spolo\u010dnosti \u013eud\u00ed, s ktor\u00fdmi budete zdie\u013ea\u0165 jazdu. <\/p>\n\n\n\n

A ak potrebujete nejak\u00fd d\u00f4kaz o tom, \u017ee LSD je \"cult\", sta\u010d\u00ed si spomen\u00fa\u0165 na psychedelick\u00e9ho hrdinu Timothy Leary<\/a><\/strong>. <\/strong> Leary zalo\u017eil vlastn\u00fa \"cirkev\" s n\u00e1zvom Liga za duchovn\u00fd objav, ktorej sviatos\u0165ou bolo LSD. V skuto\u010dnosti je ve\u013ea pr\u00edbehov o skupin\u00e1ch outsiderov s\u00fastreden\u00fdch okolo tejto rozkladnej l\u00e1tky.<\/p>\n\n\n\n

Tajn\u00e1 om\u00e1\u010dka <\/em><\/h2>\n\n\n\n

Nahum Sonenberg<\/strong>, spoluautor a profesor bioch\u00e9mie na McGillovej univerzite, povedal, \u017ee v\u017edy vedeli, \u017ee LSD vyvol\u00e1va \u0161\u0165astn\u00e9 my\u0161lienky. Ale aby skuto\u010dne identifikovali \"tajn\u00fa om\u00e1\u010dku\", tak\u00fa, ktor\u00e1 by mo\u017eno mohla vylie\u010di\u0165 soci\u00e1lnu \u00fazkos\u0165? To im vyrazilo dych.<\/p>\n\n\n\n

Vedci zistili, \u017ee LSD zap\u00edna \"sp\u00edna\u010d\" pre seroton\u00edn, <\/strong>alias \"horm\u00f3n \u0161\u0165astia\". To vzru\u0161uje siln\u00fd AMPA receptory<\/strong> - siete v mozgu tak elektrizuj\u00fa, \u017ee m\u00f4\u017eu sp\u00f4sobi\u0165 epileptick\u00e9 z\u00e1chvaty.<\/p>\n\n\n\n

\u010co v\u0161ak LSD skuto\u010dne men\u00ed, je to, \u017ee preb\u00fadza tret\u00ed prote\u00edn, tzv. mTORC 1<\/strong>. A viete, \u010do sa stane, ke\u010f sa v\u0161etky tri - seroton\u00edn, AMPA a mTORC - prebudia v rovnakom \u010dase? Za\u010dnete poci\u0165ova\u0165 rozmazan\u00e9 chm\u00fd\u0159\u00ed. Akoby bol svet va\u0161ou \u00fastricou. Akoby ka\u017ed\u00fd je v\u00e1\u0161 priate\u013e. <\/em><\/p>\n\n\n\n

\"Cestn\u00e1
prostredn\u00edctvom Creative Commons<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Dr. Danilo de Gregorio<\/strong>, prv\u00fd autor \u0161t\u00fadie a postdoktorand na neurobiologickom oddelen\u00ed McGill, povedal:<\/p>\n\n\n\n

\"Tieto tri faktory spolo\u010dne podporuj\u00fa soci\u00e1lnu interakciu u my\u0161\u00ed, ktor\u00e1 je ekvivalentom empatie a soci\u00e1lneho spr\u00e1vania u \u013eud\u00ed.<\/em><\/p>\n\n\n\n

\"Doch\u00e1dza k zv\u00fd\u0161eniu spolo\u010denskosti.\"<\/em><\/p>\n\n\n\n

Mikrod\u00e1vka pre Mickeyho<\/em><\/h2>\n\n\n\n

T\u00edm robil pokusy na my\u0161iach rozdelen\u00fdch do 2 skup\u00edn. <\/p>\n\n\n\n

Prv\u00e1 skupina my\u0161\u00ed dostala mikrod\u00e1vka LSD<\/strong>, opakovane po\u010das 7 dn\u00ed. Druh\u00e1 skupina my\u0161\u00ed, ktor\u00e1 bola kontrolnou skupinou, dostala len \"nosi\u010d\" (bez LSD).<\/em> To umo\u017enilo vedcom porovna\u0165 skupinu spolo\u010densk\u00fdch tvorov s<\/em> LSD, proti inej bez <\/em>LSD. <\/p>\n\n\n\n

\u010co sa teda stalo?<\/strong><\/p>\n\n\n\n

\"hned\u00e1
Foto: Kanashi on Unsplash<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

Pomocou met\u00f3dy s n\u00e1zvom optogenetika<\/strong>v\u00fdskumn\u00edci vykonali na my\u0161iach s\u00e9riu testov. Do ka\u017edej my\u0161i bolo vlo\u017een\u00e9 mal\u00e9 optick\u00e9 vl\u00e1kno. T\u00fdm sa sledovalo, ako s\u00fa \"nad\u0161en\u00e9\" zo socializ\u00e1cie. O sedem dn\u00ed nesk\u00f4r boli my\u0161i lie\u010den\u00e9 LSD, aby sa zistilo, ako \u010dasto sa pozdravia s priate\u013eom - \u010di sa v\u00f4bec pote\u0161ia, ke\u010f ho uvidia? A h\u00e1dajte \u010do?<\/p>\n\n\n\n

My\u0161i na kyseline vy\u010derpan\u00fd<\/strong> viac \u010dasu s cudzou my\u0161ou<\/strong>, v porovnan\u00ed s t\u00fdmi, ktor\u00ed neboli lie\u010den\u00ed. Mohla by by\u0165 oby\u010dajn\u00e1 mikrod\u00e1vka* naozaj \u017ee <\/em>\u00fa\u010dinn\u00fd tak r\u00fdchlo? <\/p>\n\n\n\n

(*Zvy\u010dajne zvierat\u00e1 dost\u00e1vaj\u00fa 100-200 mcg\/kg. V tejto \u0161t\u00fadii v\u0161ak dost\u00e1vali len 30 mcg\/kg denne, aby sa vyhli halucin\u00e1ci\u00e1m.)<\/em><\/p>\n\n\n\n

Liek na plachos\u0165<\/em><\/h2>\n\n\n\n

Len si predstavte, \u017ee by tieto poznatky mohli pou\u017ei\u0165 aj pre \u013eud\u00ed! Je na obzore liek na plachos\u0165 na b\u00e1ze LSD? Dr. Gabriella Gobbi<\/strong>, psychiater a spoluautor \u0161t\u00fadie, si ur\u010dite mysl\u00ed, \u017ee je to mo\u017en\u00e9.<\/p>\n\n\n\n

\"Tieto halucinog\u00e9nne zl\u00fa\u010deniny - ktor\u00e9 v n\u00edzkych d\u00e1vkach dok\u00e1\u017eu zv\u00fd\u0161i\u0165 sociabilitu - n\u00e1m m\u00f4\u017eu pom\u00f4c\u0165 lep\u0161ie pochopi\u0165 farmakol\u00f3giu a neurobiol\u00f3giu soci\u00e1lneho spr\u00e1vania a v kone\u010dnom d\u00f4sledku vyvin\u00fa\u0165 a objavi\u0165 nov\u00e9 a bezpe\u010dnej\u0161ie lieky na lie\u010dbu du\u0161evn\u00fdch por\u00fach.\"<\/em><\/p>\n\n\n\n

<\/strong>LSD: Syntetick\u00e9 psychedelikum, ktor\u00e9 treba porazi\u0165?<\/em><\/h2>\n\n\n\n

Psychedelik\u00e1 s\u00fa fantastick\u00fdm sp\u00f4sobom \u00faniku z reality. Predt\u00fdm, ako sa vyd\u00e1te na \u00fa\u017easn\u00fd v\u00fdlet, vedzte, \u017ee va\u0161e z\u00e1\u017eitky sa m\u00f4\u017eu a bud\u00fa l\u00ed\u0161i\u0165 v z\u00e1vislosti od toho, ktor\u00fd halucinog\u00e9n si vyberiete. <\/p>\n\n\n\n

\"Chemick\u00fd
Obr\u00e1zok od Colin Behrens z Pixabay<\/mark><\/em><\/figcaption><\/figure>\n\n\n\n

LSD je samozrejme laborat\u00f3rne vyroben\u00e9, syntetizovan\u00e9 z n\u00e1me\u013eovej huby pred viac ako 80 rokmi jedn\u00fdm Albert Hofmann<\/a>. Na druhej strane psychedelik\u00e1, ktor\u00e9 sa vyskytuj\u00fa v pr\u00edrode, ako napr. magick\u00e9 huby<\/strong>, \u010darovn\u00e9 h\u013euzovky<\/strong>, ayahuasca a \u0161alvia<\/a><\/strong>, by sa mohli presk\u00fama\u0165 aj tieto \u00fa\u010dinky. Chcem poveda\u0165, \u017ee star\u00fd dobr\u00fd hr\u00edbov\u00fd trip v\u00e1m ur\u010dite m\u00f4\u017ee prinies\u0165 hrejiv\u00fd pocit pre cel\u00e9 \u013eudstvo. A \u010doko\u013evek, \u010do sa d\u00e1 urobi\u0165, aby sme spolu v\u0161etci vych\u00e1dzali o nie\u010do lep\u0161ie, nem\u00f4\u017ee by\u0165 zl\u00e9, nie?<\/p>\n\n\n\n

\u010co si mysl\u00edte? C\u00edtite sa priate\u013eskej\u0161ie, ke\u010f ste v psychedelickom vlaku? <\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Kyselina. Blotter. Kalifornia Sunshine.\u00a0<\/p>\n

Lucy in the Sky with Diamonds.<\/p>\n

Mo\u017eno ho pozn\u00e1te pod\u013ea n\u00e1zvov ul\u00edc, ktor\u00e9 v telev\u00edznych rel\u00e1ci\u00e1ch sebavedome pomen\u00favaj\u00fa kreslen\u00ed policajn\u00ed detekt\u00edvi aj \"pochybn\u00e9 postavy\". Ale nech u\u017e je jeho prez\u00fdvka ak\u00e1ko\u013evek, jedno je ist\u00e9. Nech je to u\u017e \u010doko\u013evek, v\u0161etky tie z\u00e1hady n\u00e1s len n\u00fatia vedie\u0165 viac!<\/p>","protected":false},"author":4,"featured_media":16959,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[68],"tags":[],"topics":[],"class_list":["post-16954","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-studies"],"_links":{"self":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts\/16954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/comments?post=16954"}],"version-history":[{"count":3,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts\/16954\/revisions"}],"predecessor-version":[{"id":160389,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts\/16954\/revisions\/160389"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/media\/16959"}],"wp:attachment":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/media?parent=16954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/categories?post=16954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/tags?post=16954"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/topics?post=16954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}