{"id":81939,"date":"2022-09-09T15:39:20","date_gmt":"2022-09-09T13:39:20","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=81939"},"modified":"2023-05-12T16:08:17","modified_gmt":"2023-05-12T14:08:17","slug":"3-najzaujimavejsie-pripravovane-studie-o-mikrodavkovani","status":"publish","type":"post","link":"https:\/\/www.wholecelium.com\/sk\/blog\/3-of-the-most-exciting-upcoming-microdosing-studies\/","title":{"rendered":"3 najzauj\u00edmavej\u0161ie nadch\u00e1dzaj\u00face \u0161t\u00fadie o mikrod\u00e1vkovan\u00ed"},"content":{"rendered":"

Spust\u00ed zmeny v legislat\u00edve, zb\u00fara predsudky a zmen\u00ed \u017eivoty \u013eud\u00ed trpiacich poruchami, ktor\u00e9 doned\u00e1vna nebolo mo\u017en\u00e9 \u00fa\u010dinne lie\u010di\u0165.\u00a0<\/strong><\/p>\n\n\n\n

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Foto: Moritz Kindler on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

V\u00fdskum pokra\u010duje...<\/h2>\n\n\n\n

A \u0161t\u00fadie st\u00e1le prich\u00e1dzaj\u00fa a neprest\u00e1vaj\u00fa prich\u00e1dza\u0165. Dnes sa v\u0161ak pozrieme na nieko\u013eko pripravovan\u00fdch psilocyb\u00ednov\u00fdch (a niektor\u00e9 z jeho \u010fal\u0161\u00edch psychedelick\u00fdch s\u00farodencov, ako napr. LSD<\/a>)<\/em> sk\u00fa\u0161ky, ktor\u00e9 m\u00e1me dobr\u00e9 <\/em>pocit o. A s\u00fa vodotesn\u00e9 - dvojito zaslepen\u00e9, kontrolovan\u00e9 placebom - \u00fapln\u00e1 monty. Tak ich vysk\u00fa\u0161ajme!<\/p>\n\n\n\n

Mikrod\u00e1vky psilocyb\u00ednu pri pretrv\u00e1vaj\u00facej depres\u00edvnej poruche<\/h2>\n\n\n\n

V janu\u00e1ri tohto roku, Zdravie vl\u00e1kien<\/a>, psychedelick\u00e1 spolo\u010dnos\u0165 ozn\u00e1mila kanadsk\u00fa spolupr\u00e1cu s Torontskou univerzitou. F\u00e1za 2 klinick\u00e9ho sk\u00fa\u0161ania \u00fa\u010dinku mikrod\u00e1vok psilocyb\u00ednu na pretrv\u00e1vaj\u00facu depres\u00edvnu poruchu. T\u00e1to \u0161t\u00fadia, ktorej za\u010diatok je napl\u00e1novan\u00fd na druh\u00fa polovicu roka, bude jednou z prv\u00fdch riadne kontrolovan\u00fdch \u0161t\u00fadi\u00ed, ktor\u00e9 uvid\u00edme v s\u00favislosti s mikrod\u00e1vkovan\u00edm ako lie\u010dbou depresie.<\/p>\n\n\n\n

Ak sa v \u0161t\u00fadii zist\u00ed, \u017ee mikrod\u00e1vkovanie m\u00f4\u017ee \u00faspe\u0161ne lie\u010di\u0165 depresiu, bude to vynikaj\u00faca spr\u00e1va pre mili\u00f3ny \u013eud\u00ed na celom svete, ktor\u00ed u\u017e\u00edvaj\u00fa antidepres\u00edva, vr\u00e1tane 13% v\u0161etk\u00fdch Ameri\u010danov. Aj ke\u010f trad farmaceutick\u00fdch pr\u00edpravkov do <\/em>funguj\u00fa u \u010dasti pacientov, u mnoh\u00fdch v\u0161ak nie. A pre niektor\u00fdch ved\u013eaj\u0161ie \u00fa\u010dinky nestoj\u00ed za boles\u0165.<\/p>\n\n\n\n

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Foto: Gadiel Lazcano on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Do tejto \u0161pecifickej \u0161t\u00fadie bolo zaraden\u00fdch 50 pacientov s pretrv\u00e1vaj\u00facou depres\u00edvnou poruchou. Polovica skupiny dostala 2 mg psilocyb\u00ednu a druh\u00e1 polovica placebo. Toto sa bude dia\u0165 raz t\u00fd\u017edenne po\u010das 4 t\u00fd\u017ed\u0148ov. Po skon\u010den\u00ed tohto obdobia \u0161t\u00fadie bud\u00fa v\u0161etci pacienti, vr\u00e1tane t\u00fdch, ktor\u00ed dost\u00e1vali placebo, dost\u00e1va\u0165 lie\u010dbu \u010fal\u0161ie 4 t\u00fd\u017edne. Dr\u017eme si palce, nejak\u00e9 \u00fadaje z tejto \u0161t\u00fadie budeme ma\u0165 na dosah do konca roka 2023. <\/p>\n\n\n\n

Mikrod\u00e1vky LSD pre dospel\u00fdch s ADHD<\/h2>\n\n\n\n

Mikrod\u00e1vkovanie psilocyb\u00ednu bolo ist\u00fd \u010das propagovan\u00e9 ako s\u013eubn\u00e1 podpora<\/a> pre dospel\u00fdch s ADHD. Av\u0161ak t\u00e1to \u0161t\u00fadia spolo\u010dnosti MindMed<\/a>, ktor\u00e1 bola ozn\u00e1men\u00e1 v decembri 2021, bude pou\u017e\u00edva\u0165 LSD pre svoju mikrod\u00e1vku. Ide o svetov\u00fd unik\u00e1t - sk\u00fa\u0161ku f\u00e1zy 2 na lie\u010dbu ADHD pomocou psychedelika. \u010coraz viac dospel\u00fdch dost\u00e1va diagn\u00f3zu ADHD, preto\u017ee sa o tomto ochoren\u00ed za\u010d\u00edna viac vedie\u0165. <\/p>\n\n\n\n

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Foto: Drew Dizzy Graham on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Na\u0161\u0165astie, hl\u00e1sen\u00e9 \u00fa\u010dinky mikrod\u00e1vok psychedel\u00edk sa presne zhoduj\u00fa s t\u00fdm, s \u010d\u00edm bojuj\u00fa \u013eudia s ADHD. Napr\u00edklad mnoh\u00ed dospel\u00ed s ADHD maj\u00fa probl\u00e9my so s\u00fastreden\u00edm alebo koncentr\u00e1ciou - \u010do je presne jedna z vec\u00ed, s ktor\u00fdmi m\u00e1 mikrod\u00e1vkovanie pom\u00f4c\u0165. N\u00e1ladu zlep\u0161uj\u00faca a upokojuj\u00faca sila mikrod\u00e1vok m\u00f4\u017ee tie\u017e pom\u00f4c\u0165 zmierni\u0165 nepokoj a nervozitu, ktor\u00fdmi \u010dasto trpia \u013eudia s ADHD. <\/p>\n\n\n\n

To je len nieko\u013eko hypot\u00e9z, ktor\u00e9 sa v tejto \u0161t\u00fadii sna\u017eia dok\u00e1za\u0165. D\u00fafame tie\u017e, \u017ee v pr\u00edpade \u00faspechu t\u00e1to \u0161t\u00fadia vydl\u00e1\u017edi cestu k pou\u017e\u00edvaniu LSD ako lieku na ADHD - v\u00edtanej alternat\u00edve k tradi\u010dn\u00fdm liekom na ADHD, ktor\u00e9 s\u00fa \u010dasto stimulantmi s mo\u017enos\u0165ou vzniku z\u00e1vislosti. <\/p>\n\n\n\n

\u0160t\u00fadie sa z\u00fa\u010dastn\u00ed 52 dospel\u00fdch s ADHD. Bud\u00fa dost\u00e1va\u0165 20 mikrogramov LSD alebo placebo 2x t\u00fd\u017edenne po\u010das 6 t\u00fd\u017ed\u0148ov. Prv\u00e9 \u00fadaje z tejto \u0161t\u00fadie sa o\u010dak\u00e1vaj\u00fa v druhej polovici roka 2023. <\/p>\n\n\n\n

Prebiehaj\u00faci projekt Microdose.me<\/h2>\n\n\n\n

M\u00e1me menovite<\/a> Microdose.me predt\u00fdm - ve\u010f je to najv\u00e4\u010d\u0161ia mobiln\u00e1 \u0161t\u00fadia mikrod\u00e1vkovania na svete! Na str\u00e1nke aplik\u00e1cia<\/a>, ktor\u00fa vyu\u017e\u00edva spolo\u010dnos\u0165 Quantified Citizen, mo\u017eno jednoducho pou\u017ei\u0165 na zaznamen\u00e1vanie rutinn\u00fdch postupov mikrod\u00e1vkovania a ich \u00fa\u010dinkov. Av\u0161ak pri psilocyb\u00edne \u0165a\u017ekej v\u00e1hy Paul Stamets<\/a>, a lek\u00e1rski v\u00fdskumn\u00edci ako Dr. Pamela Kryskow a Dr. Zach Walsh ako s\u00fa\u010das\u0165 t\u00edmu, bud\u00fa \u00fadaje, ktor\u00e9 zozbieraj\u00fa v spolupr\u00e1ci s pou\u017e\u00edvate\u013emi aplik\u00e1cie, pou\u017eit\u00e9 na dosiahnutie pokroku vo v\u00fdskume mikrod\u00e1vok. A u\u017e maj\u00fa<\/strong>. Od za\u010diatku \u0161t\u00fadie na konci roka 2019 sa do nej zapojilo viac ako 20 000 \u00fa\u010dastn\u00edkov z 84 kraj\u00edn a mnoh\u00e9 zistenia u\u017e boli zverejnen\u00e9. V skuto\u010dnosti len pred nieko\u013ek\u00fdmi mesiacmi vydali dokument zalo\u017een\u00fd na \u00fadajoch z aplik\u00e1cie. <\/p>\n\n\n\n

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Foto: DocuSign on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Uverejnen\u00e9 d\u0148a nature.com<\/a> 30. j\u00fana v\u00fdskum uk\u00e1zal, \u017ee u u\u017e\u00edvate\u013eov, ktor\u00ed u\u017e\u00edvali mikrod\u00e1vku psilocyb\u00ednu po\u010das 30 dn\u00ed, do\u0161lo k v\u00e4\u010d\u0161iemu zlep\u0161eniu du\u0161evn\u00e9ho zdravia, n\u00e1lady a psychomotorick\u00fdch schopnost\u00ed v porovnan\u00ed s t\u00fdmi, ktor\u00ed mikrod\u00e1vku neu\u017e\u00edvali. Zlep\u0161enie psychomotorick\u00fdch schopnost\u00ed bolo obzvl\u00e1\u0161\u0165 v\u00fdrazn\u00e9 u mikrod\u00e1vkuj\u00facich, ktor\u00ed mali viac ako 55 rokov (v porovnan\u00ed s nemikrodosermi.)<\/em> To pouk\u00e1zalo na obrovsk\u00fd potenci\u00e1l nov\u00e9ho v\u00fdskumu psilocyb\u00ednu na lie\u010dbu neurodegenerat\u00edvne ochorenia<\/a>, pre ktor\u00e9 bude ur\u010dite nasledova\u0165 \u010fal\u0161\u00ed v\u00fdskum. <\/p>\n\n\n\n

Nov\u00fd dokument v priebehu nieko\u013ek\u00fdch t\u00fd\u017ed\u0148ov<\/h3>\n\n\n\n

Skvel\u00e9 na microdose.me je, \u017ee dok\u00e1\u017ee publikova\u0165 dokumenty aj po\u010das prebiehaj\u00faceho v\u00fdskumu. Modern\u00e1 technol\u00f3gia, \u010do?! A \u010fal\u0161ie zistenia pr\u00eddu u\u017e \u010doskoro, ako Paul Stamets prezradil \u010dasopisu Doubleblind. \u010cl\u00e1nok m\u00e1 by\u0165 predlo\u017een\u00fd v \u010dasopise \"...pribli\u017ene dva t\u00fd\u017edne do dvoch recenzovan\u00fdch \u010dasopisov<\/em>.\" Z\u00e1rove\u0148 n\u00e1s podr\u00e1\u017edil l\u00e1kav\u00fdm cit\u00e1tom;<\/p>\n\n\n\n

\"Toto je jedna z najsilnej\u0161\u00edch \u0161t\u00fadi\u00ed v hist\u00f3rii lek\u00e1rskych klinick\u00fdch \u0161t\u00fadi\u00ed. Boli sme \u0161okovan\u00ed. Nikto z na\u0161ich v\u00fdskumn\u00edkov neo\u010dak\u00e1val, \u017ee \u00fadaje bud\u00fa tak\u00e9 dobr\u00e9. Mysleli sme si, \u017ee uvid\u00edme mal\u00e9 zlep\u0161enie, ale nie a\u017e tak\u00e9 vysok\u00e9 zlep\u0161enie oproti z\u00e1kladnej hodnote. Teraz u\u017e vieme, \u017ee mikrod\u00e1vkovanie psilocyb\u00ednov\u00fdch h\u00fab funguje. Je nesporn\u00e9, \u017ee to m\u00e1 pr\u00ednos.\"<\/em><\/p>\n\n\n\n

Z\u00edskajte v\u0161etky psychedelick\u00e9 aktualiz\u00e1cie tu!<\/h2>\n\n\n\n
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Foto: Landon Parenteau on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

J\u00e9\u00e9\u00e9\u00e9! Milujeme psychedelick\u00fd v\u00fdskum. Je to dar, ktor\u00fd sa st\u00e1le dar\u00ed. A vy sa m\u00f4\u017eete spo\u013eahn\u00fa\u0165, \u017ee v\u00e1m budeme tieto novinky poskytova\u0165 priebe\u017ene!  <\/p>","protected":false},"excerpt":{"rendered":"

Radi sledujeme v\u0161etky pokroky v psychedelickom v\u00fdskume. \u010ci u\u017e ide o \u0161t\u00fadie, ktor\u00e9 ukazuj\u00fa, \u017ee psilocyb\u00edn je \u00fa\u010dinnej\u0161\u00ed ako \u0161tandardn\u00e9 antidepres\u00edva ve\u013ekej farmaceutickej spolo\u010dnosti, alebo in\u00e9, ktor\u00e9 sk\u00famaj\u00fa pou\u017eitie psilocyb\u00ednu na lie\u010dbu vyhorenia, ktor\u00fdm trpia na\u0161i d\u00f4le\u017eit\u00ed zdravotn\u00edcki pracovn\u00edci, je to v\u0161etko fascinuj\u00faca cesta do bud\u00facnosti du\u0161evnej starostlivosti.<\/p>","protected":false},"author":4,"featured_media":81957,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[88],"tags":[],"topics":[],"class_list":["post-81939","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-psychedelic-studies"],"_links":{"self":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts\/81939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/comments?post=81939"}],"version-history":[{"count":4,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts\/81939\/revisions"}],"predecessor-version":[{"id":124079,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/posts\/81939\/revisions\/124079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/media\/81957"}],"wp:attachment":[{"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/media?parent=81939"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/categories?post=81939"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/tags?post=81939"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.wholecelium.com\/sk\/wp-json\/wp\/v2\/topics?post=81939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}